Module 4 – Sepsis and COVID-19 Update

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The coronavirus disease 2019 (COVID-19) pandemic, due to the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has caused a worldwide sudden and substantial increase in hospitalizations for pneumonia with multiorgan disease.

COVID-19 can cause sepsis by triggering a response from the immune system, leading to increased inflammation, and eventually organ failure. Patients with COVID-19 can contract secondary bacterial infections, making them more vulnerable to sepsis. The differences among SIRS, Sepsis, Severe Sepsis and Septic Shock are important and vital to plan the management of patient care.

Objectives

Upon conclusion of this module, participants should be able to understand:

  • Epidemiology, Pathophysiology and Diagnosis of Sepsis
  • Importance of Early Goal Directed Therapy
  • Damage control resuscitation and fluids
  • Pathophysiology and Diagnosis of COVID-19
  • Host Defense against SARS-CoV-2

Contributors

Priya Gupta MD MPH
Instructor in Medicine, Harvard Medical School
Division of General Internal Medicine
Massachusetts General Hospital
Boston, Massachusetts, USA

Jaya Pradhan DMD MPH MD
Department of Medicine, Division of Hematology and Oncology
Columbia University Medical Center
New York, USA

Reshma Tiwari MD DNB PDCC
Director Intensive Care Artemis Hospital
Gurgaon, India